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The pioneering role of PRDM9 indel mutations in tarsier evolution
PRDM9 is currently the sole speciation gene found in vertebrates causing hybrid sterility probably due to incompatible alleles. Its role in defining the double strand break loci during the meiotic prophase I is crucial for proper chromosome segregation. Therefore, the rapid turnover of the loci dete...
Autores principales: | Heerschop, Sacha, Zischler, Hans, Merker, Stefan, Perwitasari-Farajallah, Dyah, Driller, Christine |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5048142/ https://www.ncbi.nlm.nih.gov/pubmed/27698394 http://dx.doi.org/10.1038/srep34618 |
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