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Photodynamic N-TiO(2) Nanoparticle Treatment Induces Controlled ROS-mediated Autophagy and Terminal Differentiation of Leukemia Cells

In this study, we used nitrogen-doped titanium dioxide (N-TiO(2)) NPs in conjugation with visible light, and show that both reactive oxygen species (ROS) and autophagy are induced by this novel NP-based photodynamic therapy (PDT) system. While well-dispersed N-TiO(2) NPs (≤100 μg/ml) were inert, the...

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Detalles Bibliográficos
Autores principales: Moosavi, Mohammad Amin, Sharifi, Maryam, Ghafary, Soroush Moasses, Mohammadalipour, Zahra, Khataee, Alireza, Rahmati, Marveh, Hajjaran, Sadaf, Łos, Marek J., Klonisch, Thomas, Ghavami, Saeid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5048164/
https://www.ncbi.nlm.nih.gov/pubmed/27698385
http://dx.doi.org/10.1038/srep34413