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The ubiquitin ligase TRIM27 functions as a host restriction factor antagonized by Mycobacterium tuberculosis PtpA during mycobacterial infection

Macrophage-mediated innate immune responses play crucial roles in host defense against pathogens. Recent years have seen an explosion of host proteins that act as restriction factors blocking viral replication in infected cells. However, the essential factors restricting Mycobacterium tuberculosis (...

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Detalles Bibliográficos
Autores principales: Wang, Jing, Teng, Jade L. L., Zhao, Dongdong, Ge, Pupu, Li, Bingxi, Woo, Patrick C. Y., Liu, Cui Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5048167/
https://www.ncbi.nlm.nih.gov/pubmed/27698396
http://dx.doi.org/10.1038/srep34827