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Microbial Degradation of Cellular Kinases Impairs Innate Immune Signaling and Paracrine TNFα Responses
The NFκB and MAPK signaling pathways are critical components of innate immunity that orchestrate appropriate immune responses to control and eradicate pathogens. Their activation results in the induction of proinflammatory mediators, such as TNFα a potent bioactive molecule commonly secreted by recr...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5048168/ https://www.ncbi.nlm.nih.gov/pubmed/27698456 http://dx.doi.org/10.1038/srep34656 |