Hierarchical phosphorylation of apical membrane antigen 1 is required for efficient red blood cell invasion by malaria parasites

Central to the pathogenesis of malaria is the proliferation of Plasmodium falciparum parasites within human erythrocytes. Parasites invade erythrocytes via a coordinated sequence of receptor-ligand interactions between the parasite and host cell. One key ligand, Apical Membrane Antigen 1 (AMA1), is...

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Detalles Bibliográficos
Autores principales: Prinz, Boris, Harvey, Katherine L., Wilcke, Louisa, Ruch, Ulrike, Engelberg, Klemens, Biller, Laura, Lucet, Isabelle, Erkelenz, Steffen, Heincke, Dorothee, Spielmann, Tobias, Doerig, Christian, Kunick, Conrad, Crabb, Brendan S., Gilson, Paul R., Gilberger, Tim W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5048298/
https://www.ncbi.nlm.nih.gov/pubmed/27698395
http://dx.doi.org/10.1038/srep34479

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5048298/
https://www.ncbi.nlm.nih.gov/pubmed/27698395
http://dx.doi.org/10.1038/srep34479

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