TM4 of the glutamate transporter GLT-1 experiences substrate-induced motion during the transport cycle

Excitatory amino acid transporter 2 (EAAT2), also known as glial glutamate transporter type 1 (GLT-1), plays an important role in maintaining the extracellular glutamate concentrations below neurotoxic levels. The highly conserved TM2 transmembrane domain of GLT-1 maintains a stable position during...

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Detalles Bibliográficos
Autores principales: Rong, Xiuliang, Tan, Feng, Wu, Xiaojuan, Zhang, Xiuping, Lu, Lingli, Zou, Xiaoming, Qu, Shaogang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5048300/
https://www.ncbi.nlm.nih.gov/pubmed/27698371
http://dx.doi.org/10.1038/srep34522

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5048300/
https://www.ncbi.nlm.nih.gov/pubmed/27698371
http://dx.doi.org/10.1038/srep34522

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