MiR-125a-3p timely inhibits oligodendroglial maturation and is pathologically up-regulated in human multiple sclerosis

In the mature central nervous system (CNS), oligodendrocytes provide support and insulation to axons thanks to the production of a myelin sheath. During their maturation to myelinating cells, oligodendroglial precursors (OPCs) follow a very precise differentiation program, which is finely orchestrat...

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Detalles Bibliográficos
Autores principales: Lecca, Davide, Marangon, Davide, Coppolino, Giusy T., Méndez, Aida Menéndez, Finardi, Annamaria, Costa, Gloria Dalla, Martinelli, Vittorio, Furlan, Roberto, Abbracchio, Maria P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5048305/
https://www.ncbi.nlm.nih.gov/pubmed/27698367
http://dx.doi.org/10.1038/srep34503

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5048305/
https://www.ncbi.nlm.nih.gov/pubmed/27698367
http://dx.doi.org/10.1038/srep34503

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