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MiR-125a-3p timely inhibits oligodendroglial maturation and is pathologically up-regulated in human multiple sclerosis
In the mature central nervous system (CNS), oligodendrocytes provide support and insulation to axons thanks to the production of a myelin sheath. During their maturation to myelinating cells, oligodendroglial precursors (OPCs) follow a very precise differentiation program, which is finely orchestrat...
Autores principales: | Lecca, Davide, Marangon, Davide, Coppolino, Giusy T., Méndez, Aida Menéndez, Finardi, Annamaria, Costa, Gloria Dalla, Martinelli, Vittorio, Furlan, Roberto, Abbracchio, Maria P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5048305/ https://www.ncbi.nlm.nih.gov/pubmed/27698367 http://dx.doi.org/10.1038/srep34503 |
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