Coenzyme A corrects pathological defects in human neurons of PANK2‐associated neurodegeneration

Pantothenate kinase‐associated neurodegeneration (PKAN) is an early onset and severely disabling neurodegenerative disease for which no therapy is available. PKAN is caused by mutations in PANK2, which encodes for the mitochondrial enzyme pantothenate kinase 2. Its function is to catalyze the first...

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Detalles Bibliográficos
Autores principales: Orellana, Daniel I, Santambrogio, Paolo, Rubio, Alicia, Yekhlef, Latefa, Cancellieri, Cinzia, Dusi, Sabrina, Giannelli, Serena G, Venco, Paola, Mazzara, Pietro G, Cozzi, Anna, Ferrari, Maurizio, Garavaglia, Barbara, Taverna, Stefano, Tiranti, Valeria, Broccoli, Vania, Levi, Sonia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5048368/
https://www.ncbi.nlm.nih.gov/pubmed/27516453
http://dx.doi.org/10.15252/emmm.201606391

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5048368/
https://www.ncbi.nlm.nih.gov/pubmed/27516453
http://dx.doi.org/10.15252/emmm.201606391

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