Cargando…
α CAR IGF‐1 vector targeting of motor neurons ameliorates disease progression in ALS mice
OBJECTIVE: We have previously described the generation of coxsackievirus and adenovirus receptor (α CAR)‐targeted vector, and shown that intramuscular delivery in mouse leg muscles resulted in specific retrograde transduction of lumbar‐motor neurons (MNs). Here, we utilized the α CAR‐targeted vector...
| Autores principales: | , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2016
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5048386/ https://www.ncbi.nlm.nih.gov/pubmed/27752511 http://dx.doi.org/10.1002/acn3.335 |