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Dysregulation of protein phosphatase 2A in parkinson disease and dementia with lewy bodies

OBJECTIVE: Protein phosphatase 2A (PP2A) is a heterotrimeric holoenzyme composed of a catalytic C subunit, a structural A subunit, and one of several regulatory B subunits that confer substrate specificity. The assembly and activity of PP2A are regulated by reversible methylation of the C subunit. α...

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Detalles Bibliográficos
Autores principales: Park, Hye‐Jin, Lee, Kang‐Woo, Park, Eun S., Oh, Stephanie, Yan, Run, Zhang, Jie, Beach, Thomas G., Adler, Charles H., Voronkov, Michael, Braithwaite, Steven P., Stock, Jeffry B., Mouradian, M. Maral
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5048387/
https://www.ncbi.nlm.nih.gov/pubmed/27752512
http://dx.doi.org/10.1002/acn3.337