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Up-regulation of miR-95-3p in hepatocellular carcinoma promotes tumorigenesis by targeting p21 expression

Hepatocellular carcinoma (HCC) is one of the most common malignant cancers. To elucidate new regulatory mechanisms for heptocarcinogenesis, we investigated the regulation of p21, a cyclin-dependent kinase (CDK) inhibitor encoded by CDKN1A, in HCC. The expression level of p21 is decreased with the pr...

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Detalles Bibliográficos
Autores principales: Ye, Jian, Yao, Yufeng, Song, Qixue, Li, Sisi, Hu, Zhenkun, Yu, Yubing, Hu, Changqing, Da, Xingwen, Li, Hui, Chen, Qiuyun, Wang, Qing K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5048429/
https://www.ncbi.nlm.nih.gov/pubmed/27698442
http://dx.doi.org/10.1038/srep34034