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Male-specific association between MT-ND4 11719 A/G polymorphism and ulcerative colitis: a mitochondria-wide genetic association study

BACKGROUND: Ulcerative colitis (UC) is a chronic inflammatory disorder of still unknown pathogenesis. Increasing evidence indicates that alterations in mitochondrial respiration and thus adenosine triphosphate (ATP) production are involved. This may contribute to mucosal energy deficiency and subseq...

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Detalles Bibliográficos
Autores principales: Dankowski, Theresa, Schröder, Torsten, Möller, Steffen, Yu, Xinhua, Ellinghaus, David, Bär, Florian, Fellermann, Klaus, Lehnert, Hendrik, Schreiber, Stefan, Franke, Andre, Sina, Christian, Ibrahim, Saleh M., König, Inke R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5048482/
https://www.ncbi.nlm.nih.gov/pubmed/27716073
http://dx.doi.org/10.1186/s12876-016-0509-1