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Minimal Residual Disease Detection and Evolved IGH Clones Analysis in Acute B Lymphoblastic Leukemia Using IGH Deep Sequencing

Acute B lymphoblastic leukemia (B-ALL) is one of the most common types of childhood cancer worldwide and chemotherapy is the main treatment approach. Despite good response rates to chemotherapy regiments, many patients eventually relapse and minimal residual disease (MRD) is the leading risk factor...

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Detalles Bibliográficos
Autores principales: Wu, Jinghua, Jia, Shan, Wang, Changxi, Zhang, Wei, Liu, Sixi, Zeng, Xiaojing, Mai, Huirong, Yuan, Xiuli, Du, Yuanping, Wang, Xiaodong, Hong, Xueyu, Li, Xuemei, Wen, Feiqiu, Xu, Xun, Pan, Jianhua, Li, Changgang, Liu, Xiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5048610/
https://www.ncbi.nlm.nih.gov/pubmed/27757113
http://dx.doi.org/10.3389/fimmu.2016.00403