Administration of AMD3100 in endotoxemia is associated with pro-inflammatory, pro-oxidative, and pro-apoptotic effects in vivo

BACKGROUND: Chemokine receptor 4 (CXCR4) is a multifunctional G protein-coupled receptor that is activated by its natural ligand, C-X-C motif chemokine 12 (CXCL12). As a likely member of the lipopolysaccharide (LPS)-sensing complex, CXCR4 is involved in pro-inflammatory cytokine production and exhib...

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Detalles Bibliográficos
Autores principales: Seemann, Semjon, Lupp, Amelie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5048674/
https://www.ncbi.nlm.nih.gov/pubmed/27716214
http://dx.doi.org/10.1186/s12929-016-0286-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5048674/
https://www.ncbi.nlm.nih.gov/pubmed/27716214
http://dx.doi.org/10.1186/s12929-016-0286-8

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