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Methylation of SOCS3 is inversely associated with metabolic syndrome in an epigenome-wide association study of obesity

Epigenetic mechanisms, including DNA methylation, mediate the interaction between gene and environment and may play an important role in the obesity epidemic. We assessed the relationship between DNA methylation and obesity in peripheral blood mononuclear cells (PBMCs) at 485,000 CpG sites across th...

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Detalles Bibliográficos
Autores principales: Ali, Omar, Cerjak, Diana, Kent, Jack W., James, Roland, Blangero, John, Carless, Melanie A., Zhang, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5048720/
https://www.ncbi.nlm.nih.gov/pubmed/27564309
http://dx.doi.org/10.1080/15592294.2016.1216284