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The Drosophila melanogaster homolog of UBE3A is not imprinted in neurons

In mammals, expression of UBE3A is epigenetically regulated in neurons and expression is restricted to the maternal copy of UBE3A. A recent report claimed that Drosophila melanogaster UBE3A homolog (Dube3a) is preferentially expressed from the maternal allele in fly brain, inferring an imprinting me...

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Detalles Bibliográficos
Autores principales: Hope, Kevin A., LeDoux, Mark S., Reiter, Lawrence T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5048722/
https://www.ncbi.nlm.nih.gov/pubmed/27599063
http://dx.doi.org/10.1080/15592294.2016.1214783