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ASK1 controls spindle orientation and positioning by phosphorylating EB1 and stabilizing astral microtubules

Orientation and positioning of the mitotic spindle are involved in dictating cell division axis and cleavage site, and play important roles in cell fate determination and tissue morphogenesis. However, how spindle movement is controlled to achieve a defined alignment within the dividing cell is not...

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Detalles Bibliográficos
Autores principales: Luo, Youguang, Ran, Jie, Xie, Songbo, Yang, Yunfan, Chen, Jie, Li, Shanshan, Shui, Wenqing, Li, Dengwen, Liu, Min, Zhou, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5048754/
https://www.ncbi.nlm.nih.gov/pubmed/27721984
http://dx.doi.org/10.1038/celldisc.2016.33