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ASK1 controls spindle orientation and positioning by phosphorylating EB1 and stabilizing astral microtubules
Orientation and positioning of the mitotic spindle are involved in dictating cell division axis and cleavage site, and play important roles in cell fate determination and tissue morphogenesis. However, how spindle movement is controlled to achieve a defined alignment within the dividing cell is not...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5048754/ https://www.ncbi.nlm.nih.gov/pubmed/27721984 http://dx.doi.org/10.1038/celldisc.2016.33 |