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Deficits in behavioral sensitization and dopaminergic responses to methamphetamine in adenylyl cyclase 1/8‐deficient mice

The cAMP/protein kinase A pathway regulates methamphetamine (METH)‐induced neuroplasticity underlying behavioral sensitization. We hypothesize that adenylyl cyclases (AC) 1/8 mediate these neuroplastic events and associated striatal dopamine regulation. Locomotor responses to METH (1 and 5 mg/kg) an...

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Detalles Bibliográficos
Autores principales: Bosse, Kelly E., Charlton, Jennifer L., Susick, Laura L., Newman, Brooke, Eagle, Andrew L., Mathews, Tiffany A., Perrine, Shane A., Conti, Alana C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5049486/
https://www.ncbi.nlm.nih.gov/pubmed/26146906
http://dx.doi.org/10.1111/jnc.13235