Nitrotriazole-based acetamides and propanamides with broad spectrum antitrypanosomal activity

3-Nitro-1H-1,2,4-triazole-based acetamides bearing a biphenyl- or a phenoxyphenyl moiety have shown remarkable antichagasic activity both in vitro and in an acute murine model, as well as substantial in vitro antileishmanial activity but lacked activity against human African trypanosomiasis. We have...

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Detalles Bibliográficos
Autores principales: Papadopoulou, Maria V., Bloomer, William D., Rosenzweig, Howard S., Wilkinson, Shane R., Szular, Joanna, Kaiser, Marcel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Editions Scientifiques Elsevier 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5049494/
https://www.ncbi.nlm.nih.gov/pubmed/27543881
http://dx.doi.org/10.1016/j.ejmech.2016.08.002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5049494/
https://www.ncbi.nlm.nih.gov/pubmed/27543881
http://dx.doi.org/10.1016/j.ejmech.2016.08.002

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