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Identification of key amino acids responsible for the distinct aggregation properties of microtubule‐associated protein 2 and tau
The carboxyl‐terminal sequence of tau composes the framework for its intracellular inclusions that appear in diverse neurodegenerative disorders known as tauopathies. However, microtubule‐associated protein 2 (MAP2), which contains a homologous carboxyl‐terminal sequence of tau, is undetectable in t...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5049617/ https://www.ncbi.nlm.nih.gov/pubmed/26134402 http://dx.doi.org/10.1111/jnc.13228 |