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Linking aptamer‐ligand binding and expression platform folding in riboswitches: prospects for mechanistic modeling and design
The power of riboswitches in regulation of bacterial metabolism derives from coupling of two characteristics: recognition and folding. Riboswitches contain aptamers, which function as biosensors. Upon detection of the signaling molecule, the riboswitch transduces the signal into a genetic decision....
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley & Sons, Inc.
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5049679/ https://www.ncbi.nlm.nih.gov/pubmed/26361734 http://dx.doi.org/10.1002/wrna.1300 |