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The Replicative Consequences of Papillomavirus E2 Protein Binding to the Origin Replication Factor ORC2
The origin recognition complex (ORC) coordinates a series of events that lead to initiation of DNA strand duplication. As a nuclear double stranded DNA plasmid, the papillomavirus (PV) genome resembles a mini-chromosome in infected cells. To initiate its replication, the viral E2 protein binds to an...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5049798/ https://www.ncbi.nlm.nih.gov/pubmed/27701460 http://dx.doi.org/10.1371/journal.ppat.1005934 |