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The Replicative Consequences of Papillomavirus E2 Protein Binding to the Origin Replication Factor ORC2

The origin recognition complex (ORC) coordinates a series of events that lead to initiation of DNA strand duplication. As a nuclear double stranded DNA plasmid, the papillomavirus (PV) genome resembles a mini-chromosome in infected cells. To initiate its replication, the viral E2 protein binds to an...

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Detalles Bibliográficos
Autores principales:	DeSmet, Marsha, Kanginakudru, Sriramana, Rietz, Anne, Wu, Wai-Hong, Roden, Richard, Androphy, Elliot J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5049798/ https://www.ncbi.nlm.nih.gov/pubmed/27701460 http://dx.doi.org/10.1371/journal.ppat.1005934

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