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Whole Genome Sequence Analysis of a Large Isoniazid-Resistant Tuberculosis Outbreak in London: A Retrospective Observational Study
BACKGROUND: A large isoniazid-resistant tuberculosis outbreak centred on London, United Kingdom, has been ongoing since 1995. The aim of this study was to investigate the power and value of whole genome sequencing (WGS) to resolve the transmission network compared to current molecular strain typing...
Autores principales: | Casali, Nicola, Broda, Agnieszka, Harris, Simon R., Parkhill, Julian, Brown, Timothy, Drobniewski, Francis |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5049847/ https://www.ncbi.nlm.nih.gov/pubmed/27701423 http://dx.doi.org/10.1371/journal.pmed.1002137 |
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