Genetic Risk Can Be Decreased: Quitting Smoking Decreases and Delays Lung Cancer for Smokers With High and Low CHRNA5 Risk Genotypes — A Meta-Analysis

BACKGROUND: Recent meta-analyses show that individuals with high risk variants in CHRNA5 on chromosome 15q25 are likely to develop lung cancer earlier than those with low-risk genotypes. The same high-risk genetic variants also predict nicotine dependence and delayed smoking cessation. It is unclear...

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Detalles Bibliográficos
Autores principales: Chen, Li-Shiun, Baker, Timothy, Hung, Rayjean J., Horton, Amy, Culverhouse, Robert, Hartz, Sarah, Saccone, Nancy, Cheng, Iona, Deng, Bo, Han, Younghun, Hansen, Helen M., Horsman, Janet, Kim, Claire, Rosenberger, Albert, Aben, Katja K., Andrew, Angeline S., Chang, Shen-Chih, Saum, Kai-Uwe, Dienemann, Hendrik, Hatsukami, Dorothy K., Johnson, Eric O., Pande, Mala, Wrensch, Margaret R., McLaughlin, John, Skaug, Vidar, van der Heijden, Erik H., Wampfler, Jason, Wenzlaff, Angela, Woll, Penella, Zienolddiny, Shanbeh, Bickeböller, Heike, Brenner, Hermann, Duell, Eric J., Haugen, Aage, Brüske, Irene, Kiemeney, Lambertus A., Lazarus, Philip, Le Marchand, Loic, Liu, Geoffrey, Mayordomo, Jose, Risch, Angela, Schwartz, Ann G., Teare, M. Dawn, Wu, Xifeng, Wiencke, John K., Yang, Ping, Zhang, Zuo-Feng, Spitz, Margaret R., Amos, Christopher I., Bierut, Laura J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5049934/
https://www.ncbi.nlm.nih.gov/pubmed/27543155
http://dx.doi.org/10.1016/j.ebiom.2016.08.012

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5049934/
https://www.ncbi.nlm.nih.gov/pubmed/27543155
http://dx.doi.org/10.1016/j.ebiom.2016.08.012

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