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Nitric Oxide-induced Activation of the Type 1 Ryanodine Receptor Is Critical for Epileptic Seizure-induced Neuronal Cell Death

Status epilepticus (SE) is a life-threatening emergency that can cause neurodegeneration with debilitating neurological disorders. However, the mechanism by which convulsive SE results in neurodegeneration is not fully understood. It has been shown that epileptic seizures produce markedly increased...

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Detalles Bibliográficos
Autores principales: Mikami, Yoshinori, Kanemaru, Kazunori, Okubo, Yohei, Nakaune, Takuya, Suzuki, Junji, Shibata, Kazuki, Sugiyama, Hiroki, Koyama, Ryuta, Murayama, Takashi, Ito, Akihiro, Yamazawa, Toshiko, Ikegaya, Yuji, Sakurai, Takashi, Saito, Nobuhito, Kakizawa, Sho, Iino, Masamitsu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5049986/
https://www.ncbi.nlm.nih.gov/pubmed/27544065
http://dx.doi.org/10.1016/j.ebiom.2016.08.020