Cargando…

Profound regulation of Na/K pump activity by transient elevations of cytoplasmic calcium in murine cardiac myocytes

Small changes of Na/K pump activity regulate internal Ca release in cardiac myocytes via Na/Ca exchange. We now show conversely that transient elevations of cytoplasmic Ca strongly regulate cardiac Na/K pumps. When cytoplasmic Na is submaximal, Na/K pump currents decay rapidly during extracellular K...

Descripción completa

Detalles Bibliográficos
Autores principales: Lu, Fang-Min, Deisl, Christine, Hilgemann, Donald W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5050017/
https://www.ncbi.nlm.nih.gov/pubmed/27627745
http://dx.doi.org/10.7554/eLife.19267