Inhibiting poly(ADP-ribosylation) improves axon regeneration

The ability of a neuron to regenerate its axon after injury depends in part on its intrinsic regenerative potential. Here, we identify novel intrinsic regulators of axon regeneration: poly(ADP-ribose) glycohodrolases (PARGs) and poly(ADP-ribose) polymerases (PARPs). PARGs, which remove poly(ADP-ribo...

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Detalles Bibliográficos
Autores principales: Byrne, Alexandra B, McWhirter, Rebecca D, Sekine, Yuichi, Strittmatter, Stephen M, Miller, David M, Hammarlund, Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2016
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5050021/
https://www.ncbi.nlm.nih.gov/pubmed/27697151
http://dx.doi.org/10.7554/eLife.12734

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5050021/
https://www.ncbi.nlm.nih.gov/pubmed/27697151
http://dx.doi.org/10.7554/eLife.12734

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