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Inhibiting poly(ADP-ribosylation) improves axon regeneration

The ability of a neuron to regenerate its axon after injury depends in part on its intrinsic regenerative potential. Here, we identify novel intrinsic regulators of axon regeneration: poly(ADP-ribose) glycohodrolases (PARGs) and poly(ADP-ribose) polymerases (PARPs). PARGs, which remove poly(ADP-ribo...

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Detalles Bibliográficos
Autores principales:	Byrne, Alexandra B, McWhirter, Rebecca D, Sekine, Yuichi, Strittmatter, Stephen M, Miller, David M, Hammarlund, Marc
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2016
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5050021/ https://www.ncbi.nlm.nih.gov/pubmed/27697151 http://dx.doi.org/10.7554/eLife.12734

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