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Human kinetochores are swivel joints that mediate microtubule attachments

Chromosome segregation is a mechanical process that requires assembly of the mitotic spindle – a dynamic microtubule-based force-generating machine. Connections to this spindle are mediated by sister kinetochore pairs, that form dynamic end-on attachments to microtubules emanating from opposite spin...

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Detalles Bibliográficos
Autores principales: Smith, Chris A, McAinsh, Andrew D, Burroughs, Nigel J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5050023/
https://www.ncbi.nlm.nih.gov/pubmed/27591356
http://dx.doi.org/10.7554/eLife.16159