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Epigenetic silencing of miR-124 prevents spermine oxidase regulation: Implications for Helicobacter pylori-induced gastric cancer

Chronic inflammation contributes to the development of various forms of cancer. The polyamine catabolic enzyme spermine oxidase (SMOX) is induced in chronic inflammatory conditions, including Helicobacter pylori-associated gastritis, where its production of hydrogen peroxide contributes to DNA damag...

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Detalles Bibliográficos
Autores principales: Murray-Stewart, Tracy, Sierra, Johanna C., Piazuelo, M. Blanca, Mera, Robertino M., Chaturvedi, Rupesh, Bravo, Luis E., Correa, Pelayo, Schneider, Barbara G., Wilson, Keith T., Casero, Robert A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5050049/
https://www.ncbi.nlm.nih.gov/pubmed/27041578
http://dx.doi.org/10.1038/onc.2016.91