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Epigenetic silencing of miR-124 prevents spermine oxidase regulation: Implications for Helicobacter pylori-induced gastric cancer
Chronic inflammation contributes to the development of various forms of cancer. The polyamine catabolic enzyme spermine oxidase (SMOX) is induced in chronic inflammatory conditions, including Helicobacter pylori-associated gastritis, where its production of hydrogen peroxide contributes to DNA damag...
Autores principales: | Murray-Stewart, Tracy, Sierra, Johanna C., Piazuelo, M. Blanca, Mera, Robertino M., Chaturvedi, Rupesh, Bravo, Luis E., Correa, Pelayo, Schneider, Barbara G., Wilson, Keith T., Casero, Robert A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5050049/ https://www.ncbi.nlm.nih.gov/pubmed/27041578 http://dx.doi.org/10.1038/onc.2016.91 |
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