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Osteocytic Connexin Hemichannels Suppress Breast Cancer Growth and Bone Metastasis

Although the skeleton is one of predominant sites for breast cancer metastasis, why breast cancer cells often become dormant after homing to bone is not well understood. Here, we reported an intrinsic self-defense mechanism of bone cells against breast cancer cells: a critical role of connexin (Cx)...

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Detalles Bibliográficos
Autores principales: Zhou, Jade Z., Riquelme, Manuel A., Gu, Sumin, Kar, Rekha, Gao, Xiaoli, Sun, LuZhe, Jiang, Jean X.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5050050/
https://www.ncbi.nlm.nih.gov/pubmed/27041582
http://dx.doi.org/10.1038/onc.2016.101