NF-κB-HOTAIR axis links DNA damage response, chemoresistance and cellular senescence in ovarian cancer

The transcription factor nuclear factor kappa B (NF-κB) and the long non-coding RNA (lncRNA) HOTAIR (HOX transcript antisense RNA) play diverse functional roles in cancer. In this study, we show that upregulation of HOTAIR induced platinum resistance in ovarian cancer, and increased HOTAIR levels we...

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Detalles Bibliográficos
Autores principales: Özeş, Ali R., Miller, David F., Özeş, Osman N., Fang, Fang, Liu, Yunlong, Matei, Daniela, Huang, Tim, Nephew, Kenneth P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5050052/
https://www.ncbi.nlm.nih.gov/pubmed/27041570
http://dx.doi.org/10.1038/onc.2016.75

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5050052/
https://www.ncbi.nlm.nih.gov/pubmed/27041570
http://dx.doi.org/10.1038/onc.2016.75

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