SHP-2-upregulated ZEB1 is important for PDGFRα-driven glioma epithelial–mesenchymal transition and invasion in mice and humans

Gliomas are highly malignant brain tumors that are highly invasive and resistant to conventional therapy. Receptor tyrosine kinases (RTKs) such as PDGFRα (platelet-derived growth factor receptor-α), which show frequent aberrant activation in gliomas, are associated with a process of epithelial–mesen...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, L, Zhang, W, Li, Y, Alvarez, A, Li, Z, Wang, Y, Song, L, Lv, D, Nakano, I, Hu, B, Cheng, S-Y, Feng, H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5050071/
https://www.ncbi.nlm.nih.gov/pubmed/27041571
http://dx.doi.org/10.1038/onc.2016.100

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5050071/
https://www.ncbi.nlm.nih.gov/pubmed/27041571
http://dx.doi.org/10.1038/onc.2016.100

Ejemplares similares