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The Hsp90 Co-chaperones Sti1, Aha1, and P23 Regulate Adaptive Responses to Antifungal Azoles

Heat Shock Protein 90 (Hsp90) is essential for tumor progression in humans and drug resistance in fungi. However, the roles of its many co-chaperones in antifungal resistance are unknown. In this study, by susceptibility test of Neurospora crassa mutants lacking each of 18 Hsp90/Calcineurin system m...

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Detalles Bibliográficos
Autores principales: Gu, Xiaokui, Xue, Wei, Yin, Yajing, Liu, Hongwei, Li, Shaojie, Sun, Xianyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5050212/
https://www.ncbi.nlm.nih.gov/pubmed/27761133
http://dx.doi.org/10.3389/fmicb.2016.01571