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Prolonged Calorie Restriction Downregulates Skeletal Muscle mTORC1 Signaling Independent of Dietary Protein Intake and Associated microRNA Expression

Short-term (5–10 days) calorie restriction (CR) downregulates muscle protein synthesis, with consumption of a high protein-based diet attenuating this decline. Benefit of increase protein intake is believed to be due to maintenance of amino acid-mediated anabolic signaling through the mechanistic ta...

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Detalles Bibliográficos
Autores principales: Margolis, Lee M., Rivas, Donato A., Berrone, Maria, Ezzyat, Yassine, Young, Andrew J., McClung, James P., Fielding, Roger A., Pasiakos, Stefan M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5050214/
https://www.ncbi.nlm.nih.gov/pubmed/27761114
http://dx.doi.org/10.3389/fphys.2016.00445