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Cellular GFP Toxicity and Immunogenicity: Potential Confounders in in Vivo Cell Tracking Experiments

Green Fluorescent protein (GFP), used as a cellular tag, provides researchers with a valuable method of measuring gene expression and cell tracking. However, there is evidence to suggest that the immunogenicity and cytotoxicity of GFP potentially confounds the interpretation of in vivo experimental...

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Detalles Bibliográficos
Autores principales: Ansari, Amir Mehdi, Ahmed, A. Karim, Matsangos, Aerielle E., Lay, Frank, Born, Louis J., Marti, Guy, Harmon, John W., Sun, Zhaoli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5050239/
https://www.ncbi.nlm.nih.gov/pubmed/27435468
http://dx.doi.org/10.1007/s12015-016-9670-8