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Zebrafish small molecule screens: Taking the phenotypic plunge
Target based chemical screens are a mainstay of modern drug discovery, but the effectiveness of this reductionist approach is being questioned in light of declines in pharmaceutical R & D efficiency. In recent years, phenotypic screens have gained increasing acceptance as a complementary/alterna...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Research Network of Computational and Structural Biotechnology
2016
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5050293/ https://www.ncbi.nlm.nih.gov/pubmed/27721960 http://dx.doi.org/10.1016/j.csbj.2016.09.001 |