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Osteoactivin inhibition of osteoclastogenesis is mediated through CD44-ERK signaling
Osteoactivin is a heavily glycosylated protein shown to have a role in bone remodeling. Previous studies from our lab have shown that mutation in Osteoactivin enhances osteoclast differentiation but inhibits their function. To date, a classical receptor and a signaling pathway for Osteoactivin-media...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5050297/ https://www.ncbi.nlm.nih.gov/pubmed/27585719 http://dx.doi.org/10.1038/emm.2016.78 |