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Adenovirus-mediated Foxp3 expression in lung epithelial cells reduces airway inflammation in ovalbumin and cockroach-induced asthma model

Foxp3 is a master regulator of CD4(+)CD25(+) regulatory T-cell (Treg) function and is also a suppressor of SKP2 and HER2/ErbB2. There are an increasing number of reports describing the functions of Foxp3 in cell types other than Tregs. In this context, we evaluated the functions of Foxp3 in ovalbumi...

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Detalles Bibliográficos
Autores principales: Park, Soojin, Chung, Hwan-Suck, Shin, Dasom, Jung, Kyung-Hwa, Lee, Hyunil, Moon, Junghee, Bae, Hyunsu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5050299/
https://www.ncbi.nlm.nih.gov/pubmed/27633092
http://dx.doi.org/10.1038/emm.2016.83