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Broadly Neutralizing Hemagglutinin Stalk-Specific Antibodies Induce Potent Phagocytosis of Immune Complexes by Neutrophils in an Fc-Dependent Manner

Broadly neutralizing antibodies that recognize the conserved hemagglutinin (HA) stalk have emerged as exciting new biotherapeutic tools to combat seasonal and pandemic influenza viruses. Our general understanding of the mechanisms by which stalk-specific antibodies achieve protection is rapidly evol...

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Detalles Bibliográficos
Autores principales: Mullarkey, Caitlin E., Bailey, Mark J., Golubeva, Diana A., Tan, Gene S., Nachbagauer, Raffael, He, Wenqian, Novakowski, Kyle E., Bowdish, Dawn M., Miller, Matthew S., Palese, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5050345/
https://www.ncbi.nlm.nih.gov/pubmed/27703076
http://dx.doi.org/10.1128/mBio.01624-16