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Broadly Neutralizing Hemagglutinin Stalk-Specific Antibodies Induce Potent Phagocytosis of Immune Complexes by Neutrophils in an Fc-Dependent Manner
Broadly neutralizing antibodies that recognize the conserved hemagglutinin (HA) stalk have emerged as exciting new biotherapeutic tools to combat seasonal and pandemic influenza viruses. Our general understanding of the mechanisms by which stalk-specific antibodies achieve protection is rapidly evol...
Autores principales: | Mullarkey, Caitlin E., Bailey, Mark J., Golubeva, Diana A., Tan, Gene S., Nachbagauer, Raffael, He, Wenqian, Novakowski, Kyle E., Bowdish, Dawn M., Miller, Matthew S., Palese, Peter |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5050345/ https://www.ncbi.nlm.nih.gov/pubmed/27703076 http://dx.doi.org/10.1128/mBio.01624-16 |
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