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Neuroprotective Effects of Salidroside in the MPTP Mouse Model of Parkinson's Disease: Involvement of the PI3K/Akt/GSK3β Pathway

The degenerative loss through apoptosis of dopaminergic neurons in the substantia nigra pars compacta plays a primary role in the progression of Parkinson's disease (PD). Our in vitro experiments suggested that salidroside (Sal) could protect against 1-methyl-4-phenylpyridine-induced cell apopt...

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Detalles Bibliográficos
Autores principales: Zhang, Wei, He, Hong, Song, Hujie, Zhao, Junjie, Li, Tao, Wu, Leitao, Zhang, Xiaojun, Chen, Jianzong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5050371/
https://www.ncbi.nlm.nih.gov/pubmed/27738547
http://dx.doi.org/10.1155/2016/9450137