Multiple Non-Equivalent Interfaces Mediate Direct Activation of GABA(A) Receptors by Propofol

ABSTRACT: BACKGROUND: Propofol is a sedative agent that at clinical concentrations acts by allosterically activating or potentiating the γ-aminobutyric acid type A (GABA(A)) receptor. Mutational, modeling, and photolabeling studies with propofol and its analogues have identified potential interactio...

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Detalles Bibliográficos
Autores principales: Eaton, Megan M., Germann, Allison L., Arora, Ruby, Cao, Lily Q., Gao, Xiaoyi, Shin, Daniel J., Wu, Albert, Chiara, David C., Cohen, Jonathan B., Steinbach, Joe Henry, Evers, Alex S., Akk, Gustav
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bentham Science Publishers 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5050400/
https://www.ncbi.nlm.nih.gov/pubmed/26830963
http://dx.doi.org/10.2174/1570159X14666160202121319

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5050400/
https://www.ncbi.nlm.nih.gov/pubmed/26830963
http://dx.doi.org/10.2174/1570159X14666160202121319

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