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LC-MS Based Sphingolipidomic Study on A2780 Human Ovarian Cancer Cell Line and its Taxol-resistant Strain

Drug resistance elicited by cancer cells continue to cause huge problems world-wide, for example, tens of thousands of patients are suffering from taxol-resistant human ovarian cancer. However, its biochemical mechanisms remain unclear. Sphingolipid metabolic dysregulation has been increasingly rega...

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Detalles Bibliográficos
Autores principales: Huang, Hao, Tong, Tian-Tian, Yau, Lee-Fong, Chen, Cheng-Yu, Mi, Jia-Ning, Wang, Jing-Rong, Jiang, Zhi-Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5050431/
https://www.ncbi.nlm.nih.gov/pubmed/27703266
http://dx.doi.org/10.1038/srep34684