Epigraph: A Vaccine Design Tool Applied to an HIV Therapeutic Vaccine and a Pan-Filovirus Vaccine

Epigraph is an efficient graph-based algorithm for designing vaccine antigens to optimize potential T-cell epitope (PTE) coverage. Epigraph vaccine antigens are functionally similar to Mosaic vaccines, which have demonstrated effectiveness in preliminary HIV non-human primate studies. In contrast to...

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Detalles Bibliográficos
Autores principales: Theiler, James, Yoon, Hyejin, Yusim, Karina, Picker, Louis J., Fruh, Klaus, Korber, Bette
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5050445/
https://www.ncbi.nlm.nih.gov/pubmed/27703185
http://dx.doi.org/10.1038/srep33987

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5050445/
https://www.ncbi.nlm.nih.gov/pubmed/27703185
http://dx.doi.org/10.1038/srep33987

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