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Bone marrow mesenchymal stem cells attenuate 2,5-hexanedione-induced neuronal apoptosis through a NGF/AKT-dependent pathway

Growing evidence suggests that the increased neuronal apoptosis is involved in n-hexane-induced neuropathy. We have recently reported that bone marrow-mesenchymal stem cells-derived conditioned medium (BMSC-CM) attenuated 2,5-hexanedione (HD, the active metabolite of n-hexane)-induced apoptosis in P...

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Detalles Bibliográficos
Autores principales: Wang, Qingshan, Sun, Guohua, Gao, Chenxue, Feng, Lina, Zhang, Yan, Hao, Jie, Zuo, Enjun, Zhang, Cong, Li, Shuangyue, Piao, Fengyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5050456/
https://www.ncbi.nlm.nih.gov/pubmed/27703213
http://dx.doi.org/10.1038/srep34715