Cargando…

Bone marrow mesenchymal stem cells attenuate 2,5-hexanedione-induced neuronal apoptosis through a NGF/AKT-dependent pathway

Growing evidence suggests that the increased neuronal apoptosis is involved in n-hexane-induced neuropathy. We have recently reported that bone marrow-mesenchymal stem cells-derived conditioned medium (BMSC-CM) attenuated 2,5-hexanedione (HD, the active metabolite of n-hexane)-induced apoptosis in P...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Qingshan, Sun, Guohua, Gao, Chenxue, Feng, Lina, Zhang, Yan, Hao, Jie, Zuo, Enjun, Zhang, Cong, Li, Shuangyue, Piao, Fengyuan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5050456/ https://www.ncbi.nlm.nih.gov/pubmed/27703213 http://dx.doi.org/10.1038/srep34715

Ejemplares similares

2,5-Hexanedione mediates neuronal apoptosis through suppression of NGF via PI3K/Akt signaling in the rat sciatic nerve
por: Zuo, Enjun, et al.
Publicado: (2019)

Bone marrow mesenchymal stem cells promote remyelination in spinal cord by driving oligodendrocyte progenitor cell differentiation via TNFα/RelB-Hes1 pathway: a rat model study of 2,5-hexanedione-induced neurotoxicity
por: Li, Shuangyue, et al.
Publicado: (2021)

2,5-hexanedione induced apoptosis in mesenchymal stem cells from rat bone marrow via mitochondria-dependent caspase-3 pathway
por: CHEN, Ruolin, et al.
Publicado: (2015)

2,5-Hexanedione induced apoptosis in rat spinal cord neurons and VSC4.1 cells via the proNGF/p75NTR and JNK pathways
por: Luo, Mengxin, et al.
Publicado: (2021)

Taurine inhibits 2,5-hexanedione-induced oxidative stress and mitochondria-dependent apoptosis in PC12 cells
por: LI, Shuangyue, et al.
Publicado: (2016)

2,5-hexanedione downregulates nerve growth factor and induces neuron apoptosis in the spinal cord of rats via inhibition of the PI3K/Akt signaling pathway
por: Wang, Zhemin, et al.
Publicado: (2017)

2,5-hexanedione induced apoptosis of rat bone marrow mesenchymal stem cells by reactive oxygen species
por: Liu, Shuang, et al.
Publicado: (2016)

Bone marrow mesenchymal stem cells protect against n-hexane-induced neuropathy through beclin 1-independent inhibition of autophagy
por: Hao, Jie, et al.
Publicado: (2018)

2,5-Hexanedione induces dopaminergic neurodegeneration through integrin α(M)β2/NADPH oxidase axis-mediated microglial activation
por: Zhang, Cong, et al.
Publicado: (2018)

Correction: 2,5-Hexanedione induces dopaminergic neurodegeneration through integrin α(M)β2/NADPH oxidase axis-mediated microglial activation
por: Zhang, Cong, et al.
Publicado: (2022)

Proapoptotic effects of 2,5-hexanedione on pheochromocytoma cells via oxidative injury
por: Qi, Baoning, et al.
Publicado: (2019)

Impairment of Hepatic and Renal Functions by 2,5-Hexanedione Is Accompanied by Oxidative Stress in Rats
por: Adedara, Isaac A., et al.
Publicado: (2014)

Urinary 2,5-hexanedione excretion in cryptogenic polyneuropathy compared to the general Swedish population
por: Persson, Bodil, et al.
Publicado: (2013)

One-Pot Conversion of Cellulose into 2,5-Hexanedione in H(2)O-Tetrahydrofuran Co-Solvents
por: Shi, Ning, et al.
Publicado: (2023)

Preparation of 1-Hydroxy-2,5-hexanedione from HMF by the Combination of Commercial Pd/C and Acetic Acid
por: Yang, Yanliang, et al.
Publicado: (2020)

Hair pyrrole adducts serve as biomarkers for peripheral nerve impairment induced by 2,5-hexanedione and n-hexane in rats
por: Li, Xianjie, et al.
Publicado: (2018)

2,5-Hexanedione Affects Ovarian Granulosa Cells in Swine by Regulating the CDKN1A Gene: A Transcriptome Analysis
por: Chen, Yige, et al.
Publicado: (2023)

The Background of Mitochondrial DNA Haplogroup J Increases the Sensitivity of Leber's Hereditary Optic Neuropathy Cells to 2,5-Hexanedione Toxicity
por: Ghelli, Anna, et al.
Publicado: (2009)

Nerve growth factor (NGF) and NGF receptors in mesenchymal stem/stromal cells: Impact on potential therapies
por: Zha, Kangkang, et al.
Publicado: (2021)

Tungsten Promoted Ni/Al(2)O(3) as a Noble-Metal-Free Catalyst for the Conversion of 5-Hydroxymethylfurfural to 1-Hydroxy-2,5-Hexanedione
por: Duan, Ying, et al.
Publicado: (2022)

Activation of the NGF/TrkA signaling pathway attenuates diabetic erectile dysfunction
por: Hou, Yi, et al.
Publicado: (2017)

Subchronic Exposure to Arsenic Represses the TH/TRβ1-CaMK IV Signaling Pathway in Mouse Cerebellum
por: Guan, Huai, et al.
Publicado: (2016)

APP Regulates NGF Receptor Trafficking and NGF-Mediated Neuronal Differentiation and Survival
por: Zhang, Yun-wu, et al.
Publicado: (2013)

Correlation between Levels of 2, 5-Hexanedione and Pyrrole Adducts in Tissues of Rats Exposure to n-Hexane for 5-Days
por: Yin, Hongyin, et al.
Publicado: (2013)

Bone Marrow Mesenchymal Stem Cells Attenuate Mitochondria Damage Induced by Hypoxia in Mouse Trophoblasts
por: Wang, Lingjuan, et al.
Publicado: (2016)

Comparison of bone marrow and peripheral blood aberrant plasma cell assessment by NGF in patients with MM
por: Kriegsmann, Katharina, et al.
Publicado: (2022)

ProNGF/NGF Modulates Autophagy and Apoptosis through PI3K/Akt/mTOR and ERK Signaling Pathways following Cerebral Ischemia-Reperfusion in Rats
por: Li, Yanbo, et al.
Publicado: (2022)

Expression of NGF/proNGF and Their Receptors TrkA, p75(NTR) and Sortilin in Melanoma
por: Marsland, Mark, et al.
Publicado: (2022)

Taurine protects dopaminergic neurons in a mouse Parkinson’s disease model through inhibition of microglial M1 polarization
por: Che, Yuning, et al.
Publicado: (2018)

NGF and NGF-receptor expression of cultured immortalized human corneal endothelial cells
por: Sornelli, Federica, et al.
Publicado: (2010)

An Optimized Procedure for the Site-Directed Labeling of NGF and proNGF for Imaging Purposes
por: Di Matteo, Pierluigi, et al.
Publicado: (2017)

Spinal Mobilization Prevents NGF-Induced Trunk Mechanical Hyperalgesia and Attenuates Expression of CGRP
por: Reed, William R., et al.
Publicado: (2020)

NGF : hacia una nueva frontera en la neurobiología /
por: Levi-Montalcini, Rita
Publicado: (1993)

NGF and proNGF Reciprocal Interference in Immunoassays: Open Questions, Criticalities, and Ways Forward
por: Malerba, Francesca, et al.
Publicado: (2016)

Interferon-β gene-modified human bone marrow mesenchymal stem cells attenuate hepatocellular carcinoma through inhibiting AKT/FOXO3a pathway
por: Xie, C, et al.
Publicado: (2013)

LianXia Formula Granule Attenuates Cardiac Sympathetic Remodeling in Rats with Myocardial Infarction via the NGF/TrKA/PI3K/AKT Signaling Pathway
por: Li, Sai-Sai, et al.
Publicado: (2021)

Conformational Plasticity of proNGF
por: Paoletti, Francesca, et al.
Publicado: (2011)

NGF, Brain and Behavioral Plasticity
por: Berry, Alessandra, et al.
Publicado: (2012)

Celecoxib attenuates hepatosteatosis by impairing de novo lipogenesis via Akt‐dependent lipogenic pathway
por: Zhang, Cong, et al.
Publicado: (2022)

Role and regulation of Cdc25A phosphatase in neuron death induced by NGF deprivation or β-amyloid
por: Chatterjee, Nandini, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_30quqcechcvlei15bco6lm8et5